
Technician (BTA/MTA) for the DKTK research project "ASTRON" in Part Time (19,75 h/week)
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Mainz
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Technician (BTA/MTA) for the DKTK research project "ASTRON" in Part Time (19,75 h/week)
Mainz
Aktualität: 15.07.2025
Anzeigeninhalt:
15.07.2025, Deutsches Krebsforschungszentrum (DKFZ)
Mainz
Technician (BTA/MTA) for the DKTK research project "ASTRON" in Part Time (19,75 h/week)
Aufgaben:
At the DKTK partner site Frankfurt/Mainz (work location Department of Hematology and Medical Oncology at the University Medical Center Mainz), an MTA/TA is sought for the DKTK research project «ASTRON». The main task is to carry out experiments (in vitro and 3D bioprints) based on next-generation cellular interventions that can work synergistically with mRNA intervention. The candidate will separately develop interventions and test these in conjunction with mRNA patterns.
Cell culture (immune cells, tumor cell lines, but also tissue explants from fresh, healthy or cancer patients, microscopy analysis)
CAR/TCR-engineering T cells
MRNA interventions within the tumor microenvironment
DNA and mRNA preparation, PCR, Western Blotting
Functional testing (tumor cell targeting and killing by CAR/TCR-equipped T cells, analysis of T cell metabolic fitness etc.)
In vivo oncology/PDX models (mouse studies)
Maintenance of in vitro cell lines
Administration and documentation (assist with analysis of data, the preparation of research publications and reports, conduct literature searches, and also order lab supplies)
Assist in designing and planning research project-related experiments with the group leader
Performing laboratory-based research with the requirements of good laboratory practice using a range of techniques, including in immunology, cellular biology, biochemistry and lately in vivo mouse studies
Qualifikationen:
BTA, MTA or equivalent
Prior experience with cell culture and in molecular biology and biochemistry methods
Team spirit
Good German and English communication skills
Berufsfeld
Öffentlicher Dienst, Verwaltung
Pharma, Chemie, Med., Biotechn.
Forschung, Lehre
Forschung & Entwicklung
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